SCHEMBL4265757

SCHEMBL4265757

O=C(O)c1c(I)c(I)c(I)c(I)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TPMT P51580 2/20 0.39
CYP1A2 P05177 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.31
DPP4 P27487 1/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1859003 0.93 TPMT (0.39) TPMTCYP1A2CA12CA1CA2
SCHEMBL8537633 0.90 TPMT (0.38) TPMTCYP1A2CA12CA1CA2
Hydrochloric Acid SCHEMBL8824728 0.90 TPMT (0.38) TPMTCYP1A2CA12CA1CA2
SCHEMBL7596897 0.89 TPMT (0.41) TPMTCYP1A2CA12CA1CA2
Hydrochloric Acid SCHEMBL8536294 0.87 TPMT (0.36) TPMTCYP1A2CA12CA1CA2
SCHEMBL16342093 0.86 LMNA (0.34) TPMTCYP1A2LMNA
Hydrochloric Acid SCHEMBL8541347 0.86 TPMT (0.39) TPMTCYP1A2CA12CA1CA2
SCHEMBL9600105 0.86 TPMT (0.39) TPMTCYP1A2CA12CA1CA2
SCHEMBL8855992 0.86 TPMT (0.39) TPMTCYP1A2CA12CA1CA2
SCHEMBL7757117 0.84 DPP4 (0.37) TPMTCYP1A2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230097362-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL FUJI POLYMER INDUSTRIES CO., LTD. (JP) 2023-03-30 US claimed
EP-4113592-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL Fuji Polymer Industries Co., Ltd. (JP) 2023-01-04 EP claimed
CN-115362547-A Heat-conducting organic silicon heat dissipation material 富士高分子工业株式会社 2022-11-18 CN claimed
WO-2022049902-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL 富士高分子工業株式会社 2022-03-10 WO claimed
EP-2066362-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF Boston Scientific Limited (BB) 2009-06-10 EP claimed
WO-2008033198-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF BOSTON SCIENTIFIC LIMITED (BB) 2008-03-20 WO claimed
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 US claimed
US-12590236-B2 Thermally conductive silicone heat dissipation material FUJI POLYMER INDUSTRIES CO., LTD. (JP) 2026-03-31 US disclosed
US-20230097362-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL FUJI POLYMER INDUSTRIES CO., LTD. (JP) 2023-03-30 US disclosed
EP-4113592-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL Fuji Polymer Industries Co., Ltd. (JP) 2023-01-04 EP disclosed
CN-115362547-A Heat-conducting organic silicon heat dissipation material 富士高分子工业株式会社 2022-11-18 CN disclosed
WO-2022049902-A1 THERMALLY CONDUCTIVE SILICONE HEAT DISSIPATION MATERIAL 富士高分子工業株式会社 2022-03-10 WO disclosed
US-10060242-B2 Traceable metal-organic frameworks for use in subterranean formations HALLIBURTON ENERGY SERVICES, INC. (US) 2018-08-28 US disclosed
WO-2008033198-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF BOSTON SCIENTIFIC LIMITED (BB) 2008-03-20 WO disclosed
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 US disclosed
US-5851511-A Polyiodo compounds, their preparation and their use in X-ray radiology GUERBET S.A. (FR) 1998-12-22 US disclosed
EP-0746339-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES NYCOMED IMAGING AS (NO) 1996-12-11 EP disclosed
WO-1995022995-A1 X-RAY CONTRAST COMPOSITIONS CONTAINING CELLULOSE DERIVATIVES NYCOMED IMAGING A/S (NO) 1995-08-31 WO disclosed
US-4065442-A Pyrolysis compositions from silver salts of polycarboxylic acids STANDARD OIL COMPANY (US) 1977-12-27 US disclosed
US-3933869-A Preparation of organic radiohalogen compounds SCHERING AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590236-B2 Thermally conductive silicone heat dissipation material HEATR1, HSF1, HSPA4 TPMT 4777/4885CYP1A2 3595/4885CA12 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.