SCHEMBL8856057

SCHEMBL8856057

C1=C2CCCCC2NC2CCCCC12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1587906 0.63
SCHEMBL1397117 0.61 CYP19A1 (0.33)
SCHEMBL23360767 0.60 OAT (0.34)
SCHEMBL4774052 0.59 KDM1A (0.32)
SCHEMBL15997826 0.58
SCHEMBL20782381 0.58 ALDH1A1 (0.36)
SCHEMBL19992481 0.58 KMT2A (0.32)
SCHEMBL3462991 0.57
SCHEMBL2504298 0.57
SCHEMBL486040 0.57 TLR4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502733-A1 Air-activatable polymerisable compositions LOCTITE (IRELAND) Ltd. (IE) 1992-09-09 EP claimed
US-5683536-A PEROXIDE-FREE AUTOOXIDIZABLE FREE RADICAL CATALYST LOCTITE LTD. (IE) 1997-11-04 US disclosed
US-5523347-A CONTAINS PARTIALLY HYDROGENATED PYRIDINES, CONDENSATION PRODUCT OF CYCLIC KETONES AND UREAS, SCHIFF'S BASE, INDOLES, PYRROLES, IMIDAZOLES, PIPERAZINES, CARBAZOLES AND TETRAHYDROQUNOLINES AS ACTIVATOR LOCTITE (IRELAND) LIMITED (IE) 1996-06-04 US disclosed
EP-0502733-A1 Air-activatable polymerisable compositions LOCTITE (IRELAND) Ltd. (IE) 1992-09-09 EP disclosed