SCHEMBL8856832

SCHEMBL8856832

N#CC=C(C(=O)O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792038 0.84
SCHEMBL7792035 0.84
SCHEMBL17439644 0.80
SCHEMBL4019724 0.80 LMNA (0.33)
SCHEMBL9391025 0.75
SCHEMBL8847359 0.75
SCHEMBL29137403 0.73 NPSR1 (0.47)
SCHEMBL10687842 0.71
SCHEMBL82522 0.71
SCHEMBL435588 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5683618-A MIXTURES OF ESTERS, KETONES OR NITRILES FOR LUBRICANTS FOR STABILITY ALBEMARLE CORPORATION (US) 1997-11-04 US disclosed
US-5569779-A ESTER OILS; LUBRICANTS ALBEMARLE CORPORATION (US) 1996-10-29 US disclosed
US-5536872-A Michael addition process ALBEMARLE CORPORATION (US) 1996-07-16 US disclosed
US-5430177-A Polyfunctional Michael addition products ALBEMARLE CORPORATION (US) 1995-07-04 US disclosed
WO-1995014650-A1 MICHAEL REACTION ALBEMARLE CORPORATION (US) 1995-06-01 WO disclosed
EP-0618956-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ALBEMARLE CORPORATION (US) 1994-10-12 EP disclosed
US-5350875-A Michael reaction ALBEMARLE CORPORATION (US) 1994-09-27 US disclosed
WO-1993013188-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ETHYL CORPORATION (US) 1993-07-08 WO disclosed