SCHEMBL4019724

SCHEMBL4019724

C=CC(=O)C(=CC#N)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8856832 0.80
SCHEMBL7792035 0.71
SCHEMBL7792038 0.71
SCHEMBL2245946 0.69 LMNA (0.45) LMNA
SCHEMBL9642528 0.69 LMNA (0.38) LMNA
SCHEMBL2245952 0.69 LMNA (0.45) LMNA
SCHEMBL17439644 0.68
Acrylic Acid SCHEMBL28528850 0.67 LMNA (0.43) LMNA
Oxalic Acid SCHEMBL11832408 0.66 ALDH1A1 (0.60) LMNA
SCHEMBL326495 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11707550-B2 Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-25 US claimed
US-20210213159-A1 Polyphosphate-Functionalized Inorganic Nanoparticles as Hemostatic Compositions and Methods of Use THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY 2021-07-15 US claimed
EP-1626749-B1 IMPLANTS COMPRISING FUNCTIONALIZED CARBON SURFACES CINV AG (DE) 2008-10-08 EP claimed
US-20240157022-A1 Polyphosphate-Functionalized Inorganic Nanoparticles as Hemostatic Compositions and Methods of Use THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2024-05-16 US disclosed
EP-4360656-A2 POLYPHOSPHATE-FUNCTIONALIZED INORGANIC NANOPARTICLES AS HEMOSTATIC COMPOSITIONS AND METHODS OF USE The Regents of The University of California (US) 2024-05-01 EP disclosed
US-11918653-B2 Triglyceride otic formulations and uses thereof DOMPÉ FARMACEUTICI S.P.A. (IT) 2024-03-05 US disclosed
EP-3659627-B1 POLYPHOSPHATE-FUNCTIONALIZED INORGANIC NANOPARTICLES AS HEMOSTATIC COMPOSITIONS AND METHODS OF USE UNIV CALIFORNIA (US) 2024-02-14 EP disclosed
US-11707550-B2 Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-25 US disclosed
US-20210213159-A1 Polyphosphate-Functionalized Inorganic Nanoparticles as Hemostatic Compositions and Methods of Use THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY 2021-07-15 US disclosed
US-20210138069-A1 TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF DOMPÉ FARMACEUTICI S.P.A. (IT) 2021-05-13 US disclosed
US-10842908-B2 Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-11-24 US disclosed
US-20080166417-A1 Preventing intraocular pressurization; incorporating steroid as fine particles in ophthalmic formulation SANTEN PHARMACEUTICAL CO., LTD. (JP) 2008-07-10 US disclosed
WO-2008006235-A2 SCFV ANTIBODIES WHICH PASS EPITHELIAL AND/OR ENDOTHELIAL LAYERS ESBATECH AG (CH) 2008-01-17 WO disclosed
EP-1867334-A1 METHOD OF RELIEVING OR AVOIDING SIDE EFFECT OF STEROID COMPOUND SANTEN PHARMACEUTICAL CO., LTD. (JP) 2007-12-19 EP disclosed
EP-1830902-A2 COMBINATION COMPRISING AN AGENT PROVIDING A SIGNAL, AN IMPLANT MATERIAL AND A DRUG CINVENTION AG (DE) 2007-09-12 EP disclosed
CN-1829667-A Method for the production of porous carbon-based molded bodies, and use thereof as cell culture carrier systems and culture systems BLUE MEMBRANES GMBH (DE) 2006-09-06 CN disclosed
US-20060177379-A1 Composition comprising an agent providing a signal, an implant material and a drug CINVENTION AG (DE) 2006-08-10 US disclosed
WO-2006069677-A2 COMBINATION COMPRISING AN AGENT PROVIDING A SIGNAL, AN IMPLANT MATERIAL AND A DRUG CINVENTION AG (DE) 2006-07-06 WO disclosed
US-20050089545-A1 Drug delivery system for the subconjunctival administration of fine grains SANTEN PHARMACEUTICAL CO., LTD. (JP) 2005-04-28 US disclosed
EP-1484054-A1 DRUG DELIVERY SYSTEM FOR THE SUBCONJUNCTIVAL ADMINISTRATION OF FINE GRAINS SANTEN PHARMACEUTICAL CO., LTD. (JP) 2004-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210138069-A1 TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF CETP, LIPA, APOB LMNA 1183/4885
US-11918653-B2 Triglyceride otic formulations and uses thereof CETP, LIPA, APOB LMNA 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.