SCHEMBL8856837

SCHEMBL8856837

CC1=CC(C)(C)Nc2ccc(Nc3ccccc3)cc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 12/20 0.62
▸ ALDH1A1 P00352 7/20 0.58
▸ KDM4E B2RXH2 6/20 0.58
▸ HPGD P15428 6/20 0.58
▸ HSD17B10 Q99714 5/20 0.58
▸ MAPT P10636 3/20 0.58
▸ TDP1 Q9NUW8 3/20 0.57
▸ CYP3A4 P08684 3/20 0.57
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ L3MBTL1 Q9Y468 2/20 0.55
▸ MAPK1 P28482 1/20 0.54
▸ CYP1A2 P05177 2/20 0.53
▸ CYP2D6 P10635 2/20 0.53
▸ CYP2C9 P11712 2/20 0.53
▸ CYP2C19 P33261 2/20 0.53
▸ GAA P10253 1/20 0.52
▸ LMNA P02545 2/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ ALOX12 P18054 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30973137 1.00 PGR (0.62) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL31395941 0.87 KDM4E (0.72) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28300928 0.84 ALDH1A1 (0.60) PGRALDH1A1KDM4EHPGDHSD17B10
E324 SCHEMBL6354639 0.82 ALDH1A1 (0.79) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL12508056 0.80 ALDH1A1 (0.63) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3382422 0.79 KDM4E (0.58) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3378898 0.79 PGR (0.54) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL30663249 0.78 ALDH1A1 (0.44) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL27305819 0.78 ALDH1A1 (0.44) PGRALDH1A1KDM4EHPGDHSD17B10
SCHEMBL28712668 0.78 KDM4E (0.63) PGRALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61031444-A — — None — — JP disclosed
JP-60250051-A — — None — — JP disclosed
EP-3567080-B1 RUBBER COMPOSITION FOR INNER LINER AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2025-07-16 — — EP disclosed
WO-2025111343-A1 PROCESSES FOR PREPARING 6-ANILINO-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE FLEXSYS AMERICA L.P. (US) 2025-05-30 — — WO disclosed
EP-4558138-A2 AMINOINDOLE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA L.P. (US) 2025-05-28 — — EP disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 — — WO disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 — — WO disclosed
WO-2025089268-A1 POLYMER COMPOSITION, CROSSLINKED OBJECT, TIRE, AND CONJUGATED-DIENE-BASED POLYMER 株式会社ENEOSマテリアル 2025-05-01 — — WO disclosed
WO-2025057682-A1 VULCANIZED RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE 株式会社ブリヂストン 2025-03-20 — — WO disclosed
WO-2025047323-A1 RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-03-06 — — WO disclosed
EP-2910602-A2 Sidewall insert rubber composition for run-flat tire and tire produced using the composition Hankook Tire Co., Ltd. (KR) 2015-08-26 — — EP disclosed
US-20150166773-A1 RUBBER COMPOSITION OF SIDEWALL INSERT FOR RUN FLAT TIRE AND TIRE MANUFACTURED BY USING THE SAME HANKOOK TIRE CO., LTD. (KR) 2015-06-18 — — US disclosed
EP-2868491-A1 Rubber composition for tire and tire manufactured by using the same Hankook Tire Co., Ltd. (KR) 2015-05-06 — — EP disclosed
US-20150119504-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE MANUFACTURED BY USING THE SAME HANKOOK TIRE CO., LTD. (KR) 2015-04-30 — — US disclosed
CN-104448455-A High-performance tire rubber material for agriculture machine QIAOJIAN NEW ENERGY TECHNOLOGY SUZHOU CO LTD 2015-03-25 — — CN disclosed
US-20150057391-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE MANUFACTURED BY USING THE SAME HANKOOK TIRE CO., LTD. (KR) 2015-02-26 — — US disclosed
EP-2839971-A1 Rubber composition for tire tread and tire manufactured by using the same Hankook Tire Co., Ltd. (KR) 2015-02-25 — — EP disclosed
US-5684073-A BLEND OF BUTADIENE-STYRENE COPOLYMER WITH P-PHENYLENEDIAMINE AND POLYMERIC DIHYDROQUINOLINE ANTIOXIDANTS THE YOKOHAMA RUBBER CO., LTD. (JP) 1997-11-04 — — US disclosed
JP-S6131444-A ANTIOXIDANT FOR RUBBER SUMITOMO CHEM CO LTD 1986-02-13 — — JP disclosed
JP-S60250051-A RUBBER DETERIORATION INHIBITOR SUMITOMO CHEM CO LTD 1985-12-10 — — JP disclosed
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