Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857315 | 0.92 | PNP (0.49) | PNPHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8857508 | 0.90 | SMN1; SMN2 (0.51) | PNPHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8857605 | 0.89 | HTT (0.50) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7163122 | 0.88 | HTT (0.53) | PNPHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8857495 | 0.86 | KMT2A (0.51) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8857325 | 0.83 | SMN1; SMN2 (0.48) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8857794 | 0.82 | HTT (0.45) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8857503 | 0.81 | HTT (0.48) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| Bromide SCHEMBL8857613 | 0.79 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL8857586 | 0.79 | POLB (0.46) | HTTSMN1; SMN2ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658917-A | ANTIINFLAMMATION AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5648353-A | INFLAMMATORY EDEMA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| US-5624926-A | Piperidinyl-dioxoquinazolines as adenosine reuptake inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5605900-A | USEFUL FOR TREATMENT OF INFLAMMATORY EDEMA, ISCHEMIA AND REPERFUSION DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0638567-A1 | ADENOSINE INCORPORATION INHIBITOR | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1995-02-15 | — | — | EP | disclosed |