Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857623 | 0.93 | KDM4E (0.43) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857555 | 0.90 | HTT (0.45) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857368 | 0.90 | HTT (0.43) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857576 | 0.85 | HTT (0.42) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857495 | 0.83 | KMT2A (0.51) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857586 | 0.82 | POLB (0.46) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| Bromide SCHEMBL8857835 | 0.81 | ALDH1A1 (0.35) | HTTALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8857680 | 0.81 | SMN1; SMN2 (0.53) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857407 | 0.81 | SMN1; SMN2 (0.47) | KDM4EHTTUSP2XBP1SMN1; SMN2 | |
| SCHEMBL8857337 | 0.79 | HTT (0.41) | KDM4EHTTUSP2XBP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658917-A | ANTIINFLAMMATION AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5648353-A | INFLAMMATORY EDEMA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| US-5624926-A | Piperidinyl-dioxoquinazolines as adenosine reuptake inhibitors | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5605900-A | USEFUL FOR TREATMENT OF INFLAMMATORY EDEMA, ISCHEMIA AND REPERFUSION DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0638567-A1 | ADENOSINE INCORPORATION INHIBITOR | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1995-02-15 | — | — | EP | disclosed |