Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858105 | 0.93 | HTR2B (0.40) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL7306776 | 0.93 | HTR2B (0.46) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL8858148 | 0.86 | ITGB3 (0.35) | HTR2BITGB3ITGA2B | |
| SCHEMBL7311868 | 0.85 | HTR2B (0.46) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL7304230 | 0.82 | HTR2B (0.43) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL8858104 | 0.82 | ITGB3 (0.34) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL8858116 | 0.82 | KDM4E (0.35) | HTR2BITGB3ITGA2B | |
| SCHEMBL8858110 | 0.82 | ITGB3 (0.34) | HTR2BITGB3ITGA2B | |
| SCHEMBL8858160 | 0.82 | ITGB3 (0.34) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL8858159 | 0.81 | ITGB3 (0.34) | HTR2BITGB3ITGA2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |