Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858100 | 0.93 | HTR2B (0.41) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL7311868 | 0.92 | HTR2B (0.46) | HTR2BITGB3ITGA2BCYP2D6MAPT | |
| SCHEMBL7304230 | 0.89 | HTR2B (0.43) | HTR2BITGB3ITGA2BCYP2D6L3MBTL1 | |
| SCHEMBL8858105 | 0.85 | HTR2B (0.40) | HTR2BITGB3ITGA2BCYP2D6 | |
| SCHEMBL7313564 | 0.84 | ITGB3 (0.39) | HTR2BITGB3ITGA2BCYP2D6MAPT | |
| SCHEMBL7313518 | 0.82 | HTR2B (0.38) | HTR2BITGB3ITGA2BLMNA | |
| SCHEMBL7315163 | 0.79 | ITGB3 (0.38) | HTR2BITGB3ITGA2BCYP2D6MAPT | |
| SCHEMBL7308256 | 0.79 | ITGB3 (0.38) | HTR2BITGB3ITGA2BCYP2D6MAPT | |
| SCHEMBL7313170 | 0.79 | ITGB3 (0.38) | HTR2BITGB3ITGA2BCYP2D6MAPT | |
| SCHEMBL7309903 | 0.78 | ITGB3 (0.38) | HTR2BITGB3ITGA2BCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |