Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8858461

CC(CC(=O)O)C(C)(C)C(=O)O.N.N

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.36
CACNA2D1 P54289 2/20 0.34
ADRA1A P35348 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PGD P52209 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8858462 1.00 TDP1 (0.40) TDP1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL249850 0.98 TSHR (0.39) TDP1TSHRCYP2D6CYP2C19HIF1A
Tetramethylammonium Ion SCHEMBL8858617 0.91 MAPT (0.39) TDP1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL28276563 0.84 HSPD1 (0.33) TDP1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL28080184 0.80 TSHR (0.48) TSHRHIF1AALDH1A1MAPT
SCHEMBL8372729 0.78 TSHR (0.39) TDP1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL9736134 0.77 TDP1 (0.38) TDP1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL4610847 0.77 TET2 (0.33) TDP1TSHRCYP2D6CYP2C19HIF1A
Ammonia Solution, Strong SCHEMBL28464993 0.77 GABRP (0.46) TSHRCYP2D6CYP2C19HIF1AMAPT
Ammonia Solution, Strong SCHEMBL28218219 0.77 GABRP (0.46) TSHRCYP2D6CYP2C19HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9082579-A None JP disclosed
JP-H0982579-A ELECTROLYTE FOR ELECTROLYTIC CAPACITOR HITACHI AIC INC 1997-03-28 JP disclosed