Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046463 | 0.98 | PTGIR (0.62) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9048216 | 0.90 | PTGIR (0.71) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858499 | 0.90 | PTGIR (0.60) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858502 | 0.87 | PTGIR (0.60) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858624 | 0.87 | TBXAS1 (0.59) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9014526 | 0.85 | TBXAS1 (0.63) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858663 | 0.85 | TBXAS1 (0.57) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858464 | 0.85 | TBXAS1 (0.57) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9048575 | 0.85 | PTGIR (0.64) | PTGIRTBXAS1 | |
| SCHEMBL9045328 | 0.85 | PTGIR (0.64) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |