Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.63 |
| ▸ | PTGIR | P43119 | 11/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014599 | 0.93 | PTGIR (0.62) | TBXAS1PTGIRKDM4CHTR1AADRA1D | |
| SCHEMBL9014600 | 0.90 | TBXAS1 (0.60) | TBXAS1PTGIRKDM4CHTR1AADRA1D | |
| SCHEMBL9014462 | 0.89 | TBXAS1 (0.60) | TBXAS1PTGIRKDM4CHTR1AADRA1D | |
| SCHEMBL9014182 | 0.89 | TBXAS1 (0.58) | TBXAS1PTGIRKDM4C | |
| SCHEMBL9014515 | 0.88 | TBXAS1 (0.59) | TBXAS1PTGIRKDM4CPTGDR2 | |
| SCHEMBL9046463 | 0.87 | PTGIR (0.62) | TBXAS1PTGIRKDM4CPTGDR2 | |
| SCHEMBL9014331 | 0.86 | PTGIR (0.58) | TBXAS1PTGIRKDM4CHTR1AADRA1D | |
| SCHEMBL8858624 | 0.86 | TBXAS1 (0.59) | TBXAS1PTGIRKDM4CHTR1AADRA1D | |
| SCHEMBL8858499 | 0.86 | PTGIR (0.60) | TBXAS1PTGIRKDM4CPTGDR2 | |
| SCHEMBL8858482 | 0.85 | PTGIR (0.61) | TBXAS1PTGIRKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581187-B1 | Oxime derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5480998-A | Oxime derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0581187-A1 | Oxime derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |