Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.79 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.79 |
| ▸ | HTR2C | P28335 | 6/20 | 0.72 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858638 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL3946523 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3944712 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8858508 | 0.86 | MTNR1A (0.74) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8858550 | 0.86 | MTNR1A (0.57) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3327602 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8858533 | 0.84 | MTNR1A (0.76) | MTNR1AMTNR1BHTR2CNQO2 | |
| SCHEMBL3834460 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3831576 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3831492 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616614-A | USEFUL IN TREATMENT OF DISORDERS LINKED TO ABNORMAL MELATONIN ACTIVITY | ADIR ET COMPAGNIE (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |