Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.78 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.76 |
| ▸ | HTR2C | P28335 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944712 | 1.00 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CLMNACYP1A2 | |
| SCHEMBL1885895 | 0.88 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CLMNACYP1A2 | |
| SCHEMBL3327602 | 0.87 | MTNR1A (0.74) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3831576 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8858753 | 0.86 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3831492 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3834460 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4584762 | 0.85 | MTNR1A (0.82) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL4582596 | 0.84 | MTNR1A (0.84) | MTNR1AMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL5125205 | 0.84 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009022066-A2 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009022066-A2 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-02-19 | — | — | WO | disclosed |