Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858961 | 0.91 | AKR1A1 (0.48) | AKR1A1AKR1B1 | |
| SCHEMBL8984209 | 0.90 | AKR1A1 (0.48) | AKR1A1AKR1B1 | |
| SCHEMBL8858914 | 0.89 | AKR1A1 (0.43) | AKR1A1AKR1B1 | |
| SCHEMBL8658174 | 0.83 | AKR1A1 (0.51) | AKR1A1AKR1B1 | |
| SCHEMBL8858962 | 0.83 | AKR1A1 (0.47) | AKR1A1AKR1B1 | |
| SCHEMBL8984210 | 0.81 | ALDH1A1 (0.42) | AKR1A1AKR1B1 | |
| SCHEMBL8858941 | 0.81 | AKR1A1 (0.49) | AKR1A1AKR1B1 | |
| SCHEMBL8858913 | 0.80 | AKR1A1 (0.43) | AKR1A1AKR1B1 | |
| SCHEMBL8658335 | 0.78 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL8858944 | 0.78 | AKR1A1 (0.49) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700819-A | ALDOSE REDUCTASE ENZYME INHIBITOR | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0714893-A1 | 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |