Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858937 | 0.81 | AKR1B1 (0.47) | AKR1B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8658508 | 0.79 | MRGPRX4 (0.46) | AKR1B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8858952 | 0.75 | AKR1B1 (0.46) | AKR1B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11035079 | 0.74 | MEN1 (0.43) | AKR1B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11115984 | 0.70 | FOLH1 (0.61) | MEN1KMT2ANPC1RAB9AFOLH1 | |
| SCHEMBL8858923 | 0.70 | AKR1A1 (0.60) | AKR1B1 | |
| SCHEMBL30365583 | 0.70 | FOLH1 (0.76) | FOLH1SLC16A3TP53HTTPOLB | |
| SCHEMBL70392 | 0.70 | FOLH1 (0.76) | FOLH1SLC16A3TP53HTTPOLB | |
| SCHEMBL8396276 | 0.69 | MEN1 (0.47) | AKR1B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8396244 | 0.68 | AKR1B1 (0.45) | AKR1B1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700819-A | ALDOSE REDUCTASE ENZYME INHIBITOR | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |