Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787640 | 0.89 | LMNA (0.55) | LMNACYP2C19HIF1ATYMPPDE10A | |
| SCHEMBL10305674 | 0.84 | CYP2C19 (0.39) | LMNACYP2C19HIF1ATYMP | |
| SCHEMBL11291943 | 0.83 | LMNA (0.51) | LMNACYP2C19HIF1ATYMPPDE10A | |
| SCHEMBL681515 | 0.81 | LMNA (0.50) | LMNACYP2C19HIF1ATYMPPDE10A | |
| SCHEMBL29665117 | 0.78 | CYP2C19 (0.35) | LMNACYP2C19HIF1A | |
| SCHEMBL622008 | 0.78 | CYP2C19 (0.35) | LMNACYP2C19HIF1A | |
| SCHEMBL619808 | 0.77 | LMNA (0.60) | LMNACYP2C19HIF1ATYMPPDE10A | |
| SCHEMBL19261486 | 0.77 | LMNA (0.47) | LMNACYP2C19HIF1ATYMP | |
| SCHEMBL9843094 | 0.76 | LMNA (0.46) | LMNACYP2C19HIF1ATYMP | |
| Malonic Acid SCHEMBL11132766 | 0.76 | LMNA (0.48) | LMNACYP2C19HIF1ATYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470247-B1 | REVERSED PHASE CHROMATOGRAPHIC PROCESS | MALLINCKRODT INC (US) | 1997-04-16 | — | — | EP | claimed |
| CN-108947959-B | Preparation method of non-ionic iodine contrast agent intermediate | 正大天晴药业集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |