SCHEMBL681515

SCHEMBL681515

CN(CC(O)CO)C(=O)c1c(I)c(N)c(I)c(C(=O)N(C)CC(O)CO)c1I

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
TYMP P19971 1/20 0.37
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843094 0.93 LMNA (0.46) LMNACYP2C19HIF1ATYMP
Malonic Acid SCHEMBL11132766 0.93 LMNA (0.48) LMNACYP2C19HIF1ATYMP
SCHEMBL9787640 0.92 LMNA (0.55) LMNACYP2C19HIF1ATYMPPDE10A
SCHEMBL19261486 0.91 LMNA (0.47) LMNACYP2C19HIF1ATYMP
Adipic Acid SCHEMBL11497321 0.91 LMNA (0.44) LMNACYP2C19HIF1ATYMP
SCHEMBL11202227 0.89 LMNA (0.43) LMNACYP2C19HIF1ATYMP
SCHEMBL11291943 0.89 LMNA (0.51) LMNACYP2C19HIF1ATYMPPDE10A
SCHEMBL1389273 0.88 LMNA (0.67) LMNACYP2C19HIF1ATYMPPDE10A
SCHEMBL11209816 0.88 LMNA (0.43) LMNACYP2C19HIF1ATYMP
SCHEMBL11207689 0.87 LMNA (0.42) LMNACYP2C19HIF1ATYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073356-A1 REACTIVE MULTI-ARM POLYMERS HAVING BRANCHED END GROUPS BOSTON SCIENT SCIMED INC (US) 2025-03-06 US disclosed
US-12178888-B2 Reactive multi-arm polymers having branched end groups BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-12-31 US disclosed
EP-4021960-A1 REACTIVE MULTI-ARM POLYMERS HAVING BRANCHED END GROUPS Boston Scientific Scimed Inc. (US) 2022-07-06 EP disclosed
CN-114269393-A Reactive multiarm polymers with branched end groups 波士顿科学医学有限公司 2022-04-01 CN disclosed
US-20210060183-A1 REACTIVE MULTI-ARM POLYMERS HAVING BRANCHED END GROUPS BOSTON SCIENTIFIC SCIMED, INC. 2021-03-04 US disclosed
WO-2021041234-A1 REACTIVE MULTI-ARM POLYMERS HAVING BRANCHED END GROUPS BOSTON SCIENTIFIC SCIMED, INC. (US) 2021-03-04 WO disclosed
US-9738596-B2 Contrast agents GE HEALTHCARE AS (NO) 2017-08-22 US disclosed
US-9738596-B2 Contrast agents GE HEALTHCARE AS (NO) 2017-08-22 US disclosed
US-9738596-B2 Contrast agents GE HEALTHCARE AS (NO) 2017-08-22 US disclosed
US-20150191422-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2015-07-09 US disclosed
WO-2010079201-A1 CONTRAST MEDIA COMPOSITIONS GE HEALTHCARE AS (NO) 2010-07-15 WO disclosed
WO-2010079201-A1 CONTRAST MEDIA COMPOSITIONS GE HEALTHCARE AS (NO) 2010-07-15 WO disclosed
WO-2010060941-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-06-03 WO disclosed
WO-2010060941-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-06-03 WO disclosed
EP-2178568-A2 CONTRAST AGENTS GE Healthcare AS (NO) 2010-04-28 EP disclosed
WO-2009106551-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-09-03 WO disclosed
WO-2009106551-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-09-03 WO disclosed
WO-2009106552-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-09-03 WO disclosed
WO-2009008734-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-01-15 WO disclosed
WO-2009008734-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191422-A1 CONTRAST AGENTS SSTR3, INSR, INSRR LMNA 1656/4885CYP2C19 3523/4885HIF1A 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.