Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10395553 | 0.98 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL31701723 | 0.81 | PTPN1 (0.71) | KDM4EMAPTMEN1KMT2APTPN1 | |
| SCHEMBL9177960 | 0.78 | PTPN5 (0.54) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL8306430 | 0.78 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL9181607 | 0.77 | PTPN5 (0.59) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL24783724 | 0.77 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL18645723 | 0.77 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL616005 | 0.76 | FBP1 (0.65) | MAPTPTPN1PTPN5PTPN2ALDH1A1 | |
| SCHEMBL27422029 | 0.76 | MEN1 (0.56) | RAB9ANPC1SMN1; SMN2L3MBTL1STAT1 | |
| SCHEMBL4881258 | 0.76 | PTPN2 (0.55) | PTPN1PTPN5PTPN2HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056717-A1 | SUBSTITUTED BICYCLIC AMINES FOR THE TREATMENT OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-5624467-A | SLURRYING FILTER DYES, DISSOLVING, ACIDIFICATION THE MIXTURE AND DISPERSION AND MICROPRECIPITATION | EASTMAN KODAK COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0549489-A1 | Microprecipitation process for dispersing photographic filter dyes | EASTMAN KODAK COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |