Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.66 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484718 | 0.94 | MAOB (0.70) | MAOBMAOAABCB1ABCG2MEN1 | |
| SCHEMBL2485248 | 0.87 | CYP1B1 (0.71) | MAOBMAOAABCB1ABCG2MEN1 | |
| SCHEMBL9928629 | 0.83 | ABCB1 (0.59) | MAOBMAOAABCB1ABCG2MEN1 | |
| SCHEMBL8305990 | 0.80 | MAOB (0.66) | MAOBMAOAABCB1ABCG2MEN1 | |
| SCHEMBL8427265 | 0.80 | KDM4E (0.59) | ABCB1ABCG2MEN1KMT2ATP53 | |
| SCHEMBL731601 | 0.80 | ABCB1 (0.54) | ABCB1ABCG2MEN1KMT2ATP53 | |
| SCHEMBL7603349 | 0.79 | BRD4 (0.64) | MAOBMAOAABCB1ABCG2MEN1 | |
| Tetramethylluteolin SCHEMBL29572571 | 0.79 | ABCB1 (0.80) | ABCB1ABCG2MEN1KMT2ATP53 | |
| Tetramethylluteolin SCHEMBL29725288 | 0.79 | ABCB1 (0.80) | ABCB1ABCG2MEN1KMT2ATP53 | |
| Tetramethylluteolin SCHEMBL1421511 | 0.79 | ABCB1 (0.80) | ABCB1ABCG2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |