Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.70 |
| ▸ | MAOB | P27338 | 7/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484718 | 0.90 | MAOB (0.70) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL9928630 | 0.90 | CYP1B1 (0.71) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL8859633 | 0.87 | MAOB (0.66) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL29845342 | 0.85 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL1421382 | 0.85 | CYP1B1 (0.86) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL27907057 | 0.84 | CYP1B1 (0.84) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| Methane SCHEMBL27890494 | 0.84 | CYP1B1 (0.84) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL7605191 | 0.84 | CYP1B1 (0.72) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL14178914 | 0.83 | CYP1B1 (0.71) | CYP1B1CYP1A1CYP1A2MAOBMAOA | |
| SCHEMBL2483636 | 0.83 | CYP1B1 (1.00) | CYP1B1CYP1A1CYP1A2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170857-B1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULANT OF MUCUS SECRETION, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG A PHARM CO LTD (KR) | 2011-10-19 | — | — | EP | disclosed |
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD (KR) | 2010-05-27 | — | — | US | disclosed |
| EP-2170857-A2 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULANT OF MUCUS SECRETION, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong-A Pharm.Co., Ltd. (KR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008150085-A2 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULANT OF MUCUS SECRETION, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130448-A1 | 3',4',5-TRIMETHOXY FLAVONE DERIVATIVES AS STIMULATN OF MUCUS SECRETION, METHOD FOR THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | TLR5, PTN, TSLP | CYP1B1 2614/4885CYP1A1 2326/4885CYP1A2 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.