SCHEMBL8859862

SCHEMBL8859862

NC(=O)Nc1ccc(Br)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.61
ALDH1A1 P00352 2/20 0.55
MAOB P27338 1/20 0.50
PEPD P12955 1/20 0.47
IDO1 P14902 1/20 0.47
NPC1 O15118 3/20 0.46
HSD17B10 Q99714 2/20 0.44
MAPT P10636 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 2/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
GAA P10253 1/20 0.43
GFER P55789 1/20 0.43
LMNA P02545 1/20 0.42
EGFR P00533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11255183 0.84 KIF11 (0.49) KIF11ALDH1A1MAOBIDO1NPC1
SCHEMBL1137180 0.83 MAOB (0.51) KIF11ALDH1A1MAOBIDO1NPC1
SCHEMBL4795850 0.82 ALDH1A1 (0.61) ALDH1A1PEPDNPC1HSD17B10MAPT
SCHEMBL8859856 0.82 PEPD (0.52) KIF11ALDH1A1PEPDNPC1HSD17B10
SCHEMBL9335 0.81 IDO1 (0.65) ALDH1A1MAOBIDO1NPC1MAPT
SCHEMBL31223199 0.81 IDO1 (0.65) ALDH1A1MAOBIDO1NPC1MAPT
SCHEMBL14047788 0.79 ALDH1A1 (0.57) KIF11ALDH1A1PEPDNPC1HSD17B10
SCHEMBL27761090 0.79 ALDH1A1 (0.57) KIF11ALDH1A1PEPDNPC1HSD17B10
SCHEMBL24669338 0.79 MAOB (0.70) MAOBNPC1MAPTMEN1KMT2A
SCHEMBL3931647 0.79 SMN1; SMN2 (0.50) KIF11ALDH1A1MAOBIDO1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1146320-C Enhancement of seed yield of soybeans by substituted benzoyl urea 尤尼罗亚尔化学公司 2004-04-21 CN claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
CN-1272040-A Enhancement of seed yield of soybeans by substituted benzoyl urea UNIROYAL CHEM CO INC (US) 2000-11-01 CN claimed
CN-1221316-A Benzoylurea insecticides on gene-modified Bt cotton UNIROYAL CHEM CO INC (US) 1999-06-30 CN claimed
CN-1217579-C Benzoylurea insecticides on gene-modified Bt cotton UNIROYAL CHEM CO INC (US) 2005-09-07 CN disclosed
CN-1146320-C Enhancement of seed yield of soybeans by substituted benzoyl urea 尤尼罗亚尔化学公司 2004-04-21 CN disclosed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN disclosed
CN-1272040-A Enhancement of seed yield of soybeans by substituted benzoyl urea UNIROYAL CHEM CO INC (US) 2000-11-01 CN disclosed
CN-1221316-A Benzoylurea insecticides on gene-modified Bt cotton UNIROYAL CHEM CO INC (US) 1999-06-30 CN disclosed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO disclosed