Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860109 | 0.82 | KDM4E (0.50) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL31612516 | 0.82 | KDM4E (0.50) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL27898498 | 0.81 | NR3C1 (0.49) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL27656174 | 0.79 | MAPK1 (0.47) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL27966057 | 0.79 | KDM4E (0.42) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL31571874 | 0.78 | ACHE (0.41) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL11249678 | 0.75 | KDM4E (0.48) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL11449450 | 0.75 | KDM4E (0.44) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL6137016 | 0.75 | TSHR (0.53) | KDM4ETDP1CYP3A4ALOX12TSHR | |
| SCHEMBL11057310 | 0.74 | KDM4E (0.46) | KDM4ETDP1CYP3A4ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3246216-A | — | — | None | — | — | JP | disclosed |
| JP-H03246216-A | 2,4-DICHLORO-3-AMINOPHENOL-O-ACYLATED MATERIAL OR SALT THEREOF AND KERATIN FIBER DYEING AGENT COMPOSITION CONTAINING SAME MATERIAL OR SALT THEREOF | KAO CORP | 1991-11-01 | — | — | JP | disclosed |