Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617065 | 0.90 | MAPT (0.59) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL9353879 | 0.86 | MAPT (0.71) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL2238611 | 0.81 | MAPT (0.64) | ALDH1A1HTTLMNAMAPTMEN1 | |
| SCHEMBL9694766 | 0.80 | MAPT (0.62) | ALDH1A1HTTPOLBMAPTMEN1 | |
| SCHEMBL27661443 | 0.80 | APP (0.52) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL3077568 | 0.79 | CYP1A2 (0.69) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL16210999 | 0.79 | MAPT (0.69) | ALDH1A1HTTPOLBMAPTMEN1 | |
| SCHEMBL20892445 | 0.79 | RAB9A (0.56) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL9353637 | 0.76 | RAB9A (0.60) | ALDH1A1HTTLMNAPOLBMAPT | |
| SCHEMBL8860315 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637602-A | NERVOUS SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-06-10 | — | — | US | disclosed |