Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516632 | 0.89 | LOXL2 (0.40) | LOXL2MAOATAAR1 | |
| SCHEMBL19002949 | 0.83 | GRIN2D (0.36) | AGXTCYP11B1CYP11B2 | |
| SCHEMBL230856 | 0.82 | TDP1 (0.43) | LOXL2TAAR1 | |
| SCHEMBL15628871 | 0.80 | TAAR1 (0.46) | AGXTKDM1AMAOATAAR1 | |
| SCHEMBL27810951 | 0.80 | TAAR1 (0.46) | CYP11B1CYP11B2HRH3TAAR1 | |
| SCHEMBL19007863 | 0.80 | TP53 (0.48) | BCL2PTGS2 | |
| Hydrochloric Acid SCHEMBL11853156 | 0.80 | CYP3A4 (0.41) | AGXTLOXL2MAOATAAR1 | |
| Hydrochloric Acid SCHEMBL334217 | 0.80 | CYP3A4 (0.41) | AGXTLOXL2MAOATAAR1 | |
| Hydrochloric Acid SCHEMBL10899109 | 0.80 | CYP3A4 (0.41) | AGXTLOXL2MAOATAAR1 | |
| Hydrochloric Acid SCHEMBL11853139 | 0.80 | CYP3A4 (0.41) | AGXTLOXL2MAOATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5689010-A | HYDROFORMYLATION AND ALDOL CONDENSATION OF OLEFINS USING MANNICH CATALYSTS OF SECONDARY AMINE AND CARBOXYLIC ACID TO FORM ALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | claimed |
| US-5689010-A | HYDROFORMYLATION AND ALDOL CONDENSATION OF OLEFINS USING MANNICH CATALYSTS OF SECONDARY AMINE AND CARBOXYLIC ACID TO FORM ALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |