Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.36 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11853139 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL10899109 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL11853156 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL29032658 | 0.97 | CYP3A4 (0.39) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| SCHEMBL230856 | 0.97 | TDP1 (0.43) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| SCHEMBL28001089 | 0.95 | TDP1 (0.41) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| SCHEMBL27696764 | 0.95 | TDP1 (0.41) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| SCHEMBL4827020 | 0.92 | CYP3A4 (0.43) | CYP3A4TDP1CALM1TSHRALDH1A1 | |
| SCHEMBL18486679 | 0.88 | CALM1 (0.55) | CYP3A4TDP1CALM1TAAR1CA12 | |
| Diethylamine SCHEMBL5691795 | 0.85 | GAA (0.39) | CYP3A4TDP1TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556342-A | A kind of preparation method of 2,4,6 trimethyl benzoyl diphenyl base phosphine oxide | 天津久日新材料股份有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-119998379-A | Non-fluorinated resorcinol and hydroquinone analogs as curing agents for fluoroelastomers | 科慕埃弗西有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-107556342-A | A kind of preparation method of 2,4,6 trimethyl benzoyl diphenyl base phosphine oxide | 天津久日新材料股份有限公司 | 2018-01-09 | — | — | CN | disclosed |
| EP-2248849-B1 | FUSER MEMBER HAVING COMPOSITE OUTER LAYER | XEROX CORP (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2213889-B1 | An intermediate layer comprising cnt polymer nanocomposite materials in fusers | XEROX CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2275505-B1 | Hydrophobic coatings and their processes | XEROX CORP (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2248862-B1 | COATING COMPOSITION COMPRISING AN ELASTOMERIC POLYMER CONTAINING FLUORINATED NANO DIAMONDS AND FUSER MEMBER | XEROX CORP (US) | 2016-03-02 | — | — | EP | disclosed |
| US-9244406-B2 | Nanotube reinforced fluorine-containing composites | XEROX CORPORATION (US) | 2016-01-26 | — | — | US | disclosed |
| US-9069307-B2 | Fuser system for controlling static discharge | XEROX CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-8710137-B2 | Fuser member having composite outer layer | XEROX CORPORATION (US) | 2014-04-29 | — | — | US | disclosed |
| US-7732029-B1 | Compositions of carbon nanotubes | XEROX CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-20100137499-A1 | COMPOSITIONS OF CARBON NANOTUBES | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2010-06-03 | — | — | US | disclosed |
| EP-1936445-B1 | Process to prepare carbon nanotube-reinforced fluoropolymer coatings | XEROX CORP (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20100086787-A1 | NANOTUBE REINFORCED FLUORINE-CONTAINING COMPOSITES | XEROX CORPORATION (US) | 2010-04-08 | — | — | US | disclosed |
| US-20090011213-A1 | Recyclable Multilayer Thermoplastic Films and Methods of Making | GENERAL ELECTRIC COMPANY (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1942161-A1 | Compositions of carbon nanotubes | Xerox Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20080152896-A1 | PROCESS TO PREPARE CARBON NANOTUBE-REINFORCED FLUOROPOLYMER COATINGS | XEROX CORPORATION | 2008-06-26 | — | — | US | disclosed |
| US-20080152895-A1 | CARBON NANOTUBES FOR TRANSFER BELT APPLICATIONS | XEROX CORPORATION | 2008-06-26 | — | — | US | disclosed |
| EP-1936445-A1 | Process to prepare carbon nanotube-reinforced fluoropolymer coatings | Xerox Corporation (US) | 2008-06-25 | — | — | EP | disclosed |
| CN-101113796-A | Hosepipe for conveying material containing aromatic hydrocarbons solvent | SHANGHAI INST OF RUBBER PRODUC (CN) | 2008-01-30 | — | — | CN | disclosed |