Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 11/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 11/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307200 | 0.84 | NPC1 (0.43) | ALOX15CARM1PRMT6PRMT8PRMT3 | |
| SCHEMBL476364 | 0.80 | ALOX15 (0.50) | ALOX15CARM1PRMT6PRMT8PRMT3 | |
| SCHEMBL8912860 | 0.78 | NCF1 (0.38) | NPC1HRH3CHRM3SMN1; SMN2 | |
| SCHEMBL8860927 | 0.77 | NPC1 (0.31) | CARM1PRMT6PRMT8NPC1TMEM97 | |
| SCHEMBL26493952 | 0.74 | NPC1 (0.41) | NPC1GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL26493987 | 0.74 | NPC1 (0.41) | NPC1GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL25363068 | 0.73 | ALOX15 (0.41) | ALOX15CARM1PRMT6PRMT8PRMT3 | |
| SCHEMBL25365601 | 0.73 | ALOX15 (0.41) | ALOX15CARM1PRMT6PRMT8PRMT3 | |
| SCHEMBL6827945 | 0.73 | ALOX15 (0.41) | ALOX15CARM1PRMT6PRMT8PRMT3 | |
| SCHEMBL8860713 | 0.73 | RAD52 (0.53) | CARM1PRMT6PRMT8NPC1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658926-A | ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |