Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861650 | 0.87 | TAS1R3 (0.49) | ITGA4ACEMMEITGB1HPGD | |
| SCHEMBL8861647 | 0.85 | HRH4 (0.42) | ITGA4ACEMMEITGB1HPGD | |
| SCHEMBL9069632 | 0.84 | ITGA4 (0.58) | ITGA4ACEMMEITGB7CYP3A4 | |
| SCHEMBL9069634 | 0.84 | ITGA4 (0.58) | ITGA4ACEMMEITGB7CYP3A4 | |
| SCHEMBL8861579 | 0.84 | ITGA4 (0.58) | ITGA4ACEMMEITGB7CYP3A4 | |
| SCHEMBL25355213 | 0.81 | ACE (0.55) | ITGA4ACEMMEITGB1HPGD | |
| SCHEMBL9958960 | 0.81 | ACE (0.55) | ITGA4ACEMMEITGB1HPGD | |
| SCHEMBL9958965 | 0.81 | ACE (0.55) | ITGA4ACEMMEITGB1HPGD | |
| SCHEMBL9365602 | 0.79 | HPGD (0.55) | ITGA4ACEMMEITGB1HPGD | |
| Hydrochloric Acid SCHEMBL8693664 | 0.78 | HPGD (0.54) | ITGA4ACEMMEITGB1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599951-A | ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-02-04 | — | — | US | disclosed |