Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 13/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065586 | 0.90 | LTB4R (0.71) | LTB4RPTPN11 | |
| SCHEMBL8065558 | 0.83 | LTB4R (0.58) | LTB4RPTPN11 | |
| SCHEMBL8862111 | 0.82 | LTB4R (0.42) | LTB4RTSHR | |
| SCHEMBL8862008 | 0.78 | LTB4R (0.65) | LTB4R | |
| SCHEMBL8862012 | 0.77 | LTB4R (0.74) | LTB4R | |
| SCHEMBL8862075 | 0.77 | LTB4R (0.54) | LTB4R | |
| SCHEMBL27447492 | 0.77 | LTB4R (0.62) | LTB4RPTPN11 | |
| SCHEMBL8080170 | 0.77 | LTB4R (0.62) | LTB4RPTPN11 | |
| SCHEMBL9367967 | 0.77 | LTB4R (0.64) | LTB4R | |
| SCHEMBL8065566 | 0.76 | LTB4R (0.68) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |