Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862052 | 0.90 | LTB4R (0.60) | LTB4RPTPN11 | |
| SCHEMBL8862012 | 0.87 | LTB4R (0.74) | LTB4R | |
| SCHEMBL8862057 | 0.84 | LTB4R (0.51) | LTB4RPTPN11 | |
| SCHEMBL8862075 | 0.83 | LTB4R (0.54) | LTB4R | |
| SCHEMBL9490956 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9494461 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8065558 | 0.83 | LTB4R (0.58) | LTB4RPTPN11 | |
| SCHEMBL9367967 | 0.82 | LTB4R (0.64) | LTB4R | |
| SCHEMBL8862105 | 0.81 | LTB4R (0.65) | LTB4R | |
| SCHEMBL8080170 | 0.80 | LTB4R (0.62) | LTB4RPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | claimed |
| EP-0812194-B1 | Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis | SMITHKLINE BEECHAM CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |