Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.51 |
| ▸ | C5 | P01031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862111 | 0.90 | LTB4R (0.42) | LTB4RC5PPARGPPARA | |
| SCHEMBL8065586 | 0.84 | LTB4R (0.71) | LTB4RPTPN11 | |
| SCHEMBL8862079 | 0.83 | LTB4R (0.41) | LTB4RC5PTPN11PPARGPPARA | |
| SCHEMBL9335128 | 0.83 | LTB4R (0.45) | LTB4R | |
| SCHEMBL8862102 | 0.82 | LTB4R (0.44) | LTB4RC5PTPN11 | |
| SCHEMBL27373633 | 0.80 | LTB4R (0.57) | LTB4RC5 | |
| SCHEMBL8862121 | 0.79 | LTB4R (0.57) | LTB4R | |
| SCHEMBL9333856 | 0.79 | LTB4R (0.49) | LTB4RPTPN11 | |
| SCHEMBL8862132 | 0.79 | LTB4R (0.70) | LTB4R | |
| SCHEMBL27452197 | 0.79 | LTB4R (0.53) | LTB4RPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |