SCHEMBL8864003

SCHEMBL8864003

CCCCC(CCCC)(CCCC)C(O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.37
GGPS1 O95749 6/20 0.37
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CES2 O00748 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8899907 0.94 FDPS (0.34) FDPSGGPS1TSHRLMNAALDH1A1
SCHEMBL8899060 0.94 FDPS (0.44) FDPSGGPS1TSHRCES2
SCHEMBL11616812 0.88 FDPS (0.48) FDPSGGPS1TSHRCES2
SCHEMBL28250479 0.86 ALDH1A1 (0.36) FDPSGGPS1TSHRLMNAALDH1A1
SCHEMBL29588656 0.82
SCHEMBL5032751 0.80 FDPS (0.39) FDPSALDH1A1
SCHEMBL28642670 0.79 ESR1 (0.38) FDPSGGPS1TSHRLMNAALDH1A1
SCHEMBL28644619 0.77 FDPS (0.34) FDPSGGPS1TSHRLMNAALDH1A1
SCHEMBL16732296 0.77 FDPS (0.34) FDPSGGPS1TSHRLMNAALDH1A1
SCHEMBL9636778 0.76 TSHR (0.43) FDPSGGPS1TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114848585-B Improved low-toxicity high-efficiency orthoester miscible medicinal adjuvant, preparation method and local sustained-release drug delivery preparation containing adjuvant 安徽大学 2023-03-28 CN claimed
CN-114848585-A Improved low-toxicity high-efficiency orthoester miscible medicine pharmaceutic adjuvant, preparation method and local sustained-release administration preparation containing adjuvant 安徽大学 2022-08-05 CN claimed
EP-0307362-B1 Process for the manufacture of aliphatylphosphinic acid derivatives CIBA GEIGY AG (CH) 1995-02-15 EP claimed
CN-114848585-A Improved low-toxicity high-efficiency orthoester miscible medicine pharmaceutic adjuvant, preparation method and local sustained-release administration preparation containing adjuvant 安徽大学 2022-08-05 CN disclosed
CN-112513146-A Polysiloxane-polyalkylene glycol block copolymer and method for producing same 东丽株式会社 2021-03-16 CN disclosed
US-5658988-A ONE-PACKAGE; AUTOMOBILE FINISHES KANSAI PAINT CO., LTD. (JP) 1997-08-19 US disclosed
EP-0764674-A2 Fluorination of acetals, ketals and orthoesters EXFLUOR RESEARCH CORPORATION (US) 1997-03-26 EP disclosed
US-5557012-A Fluorination of acetals, ketals and orthoesters EXFLUOR RESEARCH CORPORATION (US) 1996-09-17 US disclosed
US-5543567-A Fluorination of acetals, ketals and orthoesters EXFLUOR RESEARCH CORPORATION (US) 1996-08-06 US disclosed
US-5523496-A Fluorination of acetals, ketals and orthoesters EXFLUOR RESEARCH CORPORATION (US) 1996-06-04 US disclosed
US-5300683-A Perhalogenated polyethers; lubricants; greases; high thermal and oxidative stability EXFLUOR RESEARCH CORPORATION (US) 1994-04-05 US disclosed
US-5202480-A Perfluoropolyethers and perfluorochloropolyether as lubricants, hydraulic fluids, thermal shock and vapor phase soldering fluid; nonflammable; oxidation resistance EXFLUOR RESEARCH CORPORATION (US) 1993-04-13 US disclosed
US-5053536-A Perhalogenated chlorofluoroether compounds or polyethers; lubricants EXFLUOR RESEARCH CORPORATION (US) 1991-10-01 US disclosed
EP-0436629-A1 FLUORINATION OF ACETALS, KETALS AND ORTHOESTERS EXFLUOR RESEARCH CORPORATION (US) 1991-07-17 EP disclosed
WO-1990003410-A1 FLUORINATION OF ACETALS, KETALS AND ORTHOESTERS EXFLUOR RESEARCH CORPORATION (US) 1990-04-05 WO disclosed