Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864179 | 1.00 | L3MBTL1 (0.48) | L3MBTL1CYP3A4NPSR1SIGMAR1IDO1 | |
| SCHEMBL8863668 | 0.92 | L3MBTL1 (0.50) | L3MBTL1CYP3A4NPSR1SIGMAR1 | |
| SCHEMBL8863624 | 0.91 | L3MBTL1 (0.49) | L3MBTL1CYP3A4NPSR1SIGMAR1 | |
| SCHEMBL8863589 | 0.88 | L3MBTL1 (0.53) | L3MBTL1CYP3A4NPSR1SIGMAR1 | |
| SCHEMBL21023138 | 0.85 | L3MBTL1 (0.50) | L3MBTL1CYP3A4NPSR1SIGMAR1IDO1 | |
| SCHEMBL9544416 | 0.83 | HDAC1 (0.40) | L3MBTL1 | |
| SCHEMBL9437259 | 0.83 | HDAC1 (0.40) | L3MBTL1 | |
| SCHEMBL8863692 | 0.83 | NPSR1 (0.54) | L3MBTL1CYP3A4NPSR1SIGMAR1IDO1 | |
| SCHEMBL9437264 | 0.83 | LMNA (0.43) | L3MBTL1 | |
| SCHEMBL16471969 | 0.81 | L3MBTL1 (0.57) | L3MBTL1CYP3A4NPSR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799192-A1 | METHOD FOR PREPARING DESFERRIOXAMINE B AND HOMOLOGS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5493053-A | Method for preparing desferrioxamine B and homologs thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1996-02-20 | — | — | US | disclosed |