SCHEMBL8864063

SCHEMBL8864063

COc1cc(N(c2ccccc2)c2ccccc2)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
RAB9A P51151 3/20 0.52
MAPT P10636 3/20 0.52
NPC1 O15118 2/20 0.52
NFKB1 P19838 2/20 0.52
LMNA P02545 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
MAOB P27338 1/20 0.50
SLC16A3 O15427 1/20 0.50
SLC16A1 P53985 1/20 0.50
TSHR P16473 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TP53 P04637 1/20 0.48
HTT P42858 1/20 0.47
BCHE P06276 2/20 0.45
TYR P14679 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943860 0.83 SLC16A3 (0.50) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL16000718 0.81 TUBB1 (0.47) MEN1KMT2AMAPTNPC1LMNA
SCHEMBL12288718 0.80 SLC16A3 (0.48) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL25012505 0.79 ENPP2 (0.52) MEN1KMT2AMAPTSLC16A3SLC16A1
SCHEMBL29868763 0.79 SLC16A3 (0.47) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL8943919 0.79 CA12 (0.53) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL28811544 0.79 SLC16A3 (0.47) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL14770875 0.79 SLC16A3 (0.47) MEN1KMT2AMAPTLMNASLC16A3
SCHEMBL10065711 0.77 SLC16A3 (0.46) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL1156136 0.77 MAOB (0.57) MEN1KMT2ARAB9AMAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654483-A REACTING ALKOXY-SUBSTITUTED CYCLOHEXANONE WITH DIPHENYLAMINE WHILE FORMING CYCLOHEXANONE FROM ALKOXY-SUBSTITUTED PHENOL IN PRESENCE OF SURFACE-SUPPORTED HYDROGEN TRANSFER CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1997-08-05 US disclosed