SCHEMBL1156136

SCHEMBL1156136

COc1cc(N(C)C)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
APP P05067 1/20 0.54
MMP9 P14780 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.53
MAPK1 P28482 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
RAB9A P51151 1/20 0.50
NFE2L2 Q16236 1/20 0.49
TRPA1 O75762 1/20 0.48
TRIM24 O15164 1/20 0.48
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27449776 0.94 MMP9 (0.54) MAOBAPPMMP9MEN1KMT2A
SCHEMBL1598931 0.83 NQO2 (0.49) APPMEN1KMT2AALDH1A1GAA
SCHEMBL1107760 0.80 NQO2 (0.63) MEN1KMT2AALDH1A1HPGDMAPK1
SCHEMBL19308888 0.80 MEN1 (0.51) MAOBAPPMMP9MEN1KMT2A
SCHEMBL10486146 0.79 FGFR1 (0.59) MAOBMEN1KMT2AALDH1A1MAPK1
Vanillin SCHEMBL5806547 0.78 ALDH1A1 (0.76) APPMMP9MEN1KMT2AALDH1A1
SCHEMBL8864063 0.77 MEN1 (0.54) MAOBMEN1KMT2AALDH1A1HPGD
SCHEMBL22198240 0.77 KMT2A (0.59) APPMMP9MEN1KMT2AALDH1A1
SCHEMBL9290124 0.77 NQO2 (0.46) APPMEN1KMT2AALDH1A1HPGD
SCHEMBL10485708 0.77 APP (0.53) APPMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10570138-B2 Indole AHR inhibitors and uses thereof KYN THERAPEUTICS (US) 2020-02-25 US disclosed
US-7887998-B2 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2011-02-15 US disclosed
EP-1333319-B1 Silver halide photographic light-sensitive material FUJIFILM CORP (JP) 2009-06-10 EP disclosed
EP-1521116-B1 Silver halide photographic light-sensitive material and package thereof FUJIFILM CORP (JP) 2009-01-21 EP disclosed
EP-1403698-B1 Silver halide photographic light-sensitive material comprising a particular dye, a hydrazine derivate and a benzotriazole compound FUJIFILM CORP (JP) 2008-09-03 EP disclosed
EP-1465008-B1 Silver halide photographic light-sensitive material FUJIFILM CORP (JP) 2008-07-16 EP disclosed
US-7303851-B2 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-20070224536-A1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL HIRANO MITSUNORI 2007-09-27 US disclosed
EP-1445649-B1 Silver halide photographic light-sensitive material comprising a particular dye, a hydrazine derivate and a benzotriazole compound FUJIFILM CORP (JP) 2007-08-22 EP disclosed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-6458522-B1 QUATERNARY AMMONIUM OR PHOSPHORUS SALT; ULTRA-HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 2002-10-01 US disclosed
US-20020132179-A1 Silver halide photographic light-sensitive material and processing method thereof FUJIFILM CORPORATION (JP) 2002-09-19 US disclosed
EP-1220022-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 2002-07-03 EP disclosed
EP-1217432-A2 Silver halide photographic light-sensitive material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-26 EP disclosed
US-6171753-B1 SUPPORT HAVING THEREON SPECTRALLY SENSITIZED LIGHT SENSITIVE SILVER HALIDE EMULSION LAYER CONTAINING AT LEAST TWO KINDS OF SILVER HALIDE EMULSIONS DIFFERENT IN THE CONCENTRATION OF A NITROGEN HETEROCYCLE CAPABLE OF FORMING COMPLEX WITH SILVER FUJI PHOTO FILM CO., LTD. (JP) 2001-01-09 US disclosed
US-6114081-A COMPRISING A SUPPORT HAVING THEREON AT LEAST ONE OF SPECTRALLY SENSITIZED LIGHT-SENSITIVE SILVER HALIDE EMULSION LAYERS, WHEREIN AT LEAST ONE OF THE SILVER HALIDE EMULSION LAYERS CONTAINS AT LEAST TWO KINDS OF SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JP) 2000-09-05 US disclosed
US-6048675-A DEVELOPMENT OF SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2000-04-11 US disclosed
US-5972580-A SILVER HALIDE LAYER CONTAINS HYDRAZINE DERIVATIVE, DEVELOPING SOLUTION CONTAINS ASCORBIC ACID DERIVATIVE, AMINOPHENOL DERIVATIVE, AND PYRIMIDINE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1999-10-26 US disclosed
US-5882841-A ULTRAHIGH CONTRAST, STORAGE STABILITY, UNIFORMITY, POLYMER PARTICLES CONTAINING A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
EP-0661280-A1 Novel amino acid ester and reagent composition for detecting leucocytes or elastase in body liquid KYOTO DAIICHI KAGAKU CO., LTD. (JP) 1995-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570138-B2 Indole AHR inhibitors and uses thereof AHR, ARNT, IDO1 MAOB 118/4885APP 3150/4885MMP9 2283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.