Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | MMP13 | P45452 | 2/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864471 | 0.99 | L3MBTL1 (0.33) | KMT2AMEN1L3MBTL1TLR7CYP3A4 | |
| SCHEMBL8864393 | 0.97 | KMT2A (0.34) | KMT2AMEN1L3MBTL1TLR7LMNA | |
| SCHEMBL8865230 | 0.94 | KMT2A (0.35) | KMT2AMEN1L3MBTL1TLR7LMNA | |
| SCHEMBL8864986 | 0.93 | KMT2A (0.35) | KMT2AMEN1L3MBTL1TLR7CYP3A4 | |
| SCHEMBL8864391 | 0.92 | L3MBTL1 (0.34) | KMT2AMEN1L3MBTL1TLR7CYP3A4 | |
| SCHEMBL8864495 | 0.91 | KMT2A (0.35) | KMT2AMEN1L3MBTL1TLR7LMNA | |
| SCHEMBL8864340 | 0.90 | KMT2A (0.36) | KMT2AMEN1L3MBTL1TLR7LMNA | |
| SCHEMBL8864684 | 0.90 | — | — | |
| SCHEMBL8864515 | 0.89 | ALDH1A1 (0.31) | LMNA | |
| SCHEMBL8865056 | 0.88 | TLR7 (0.33) | KMT2AMEN1L3MBTL1TLR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |