Styrene

Styrene

SCHEMBL8864892

C=CC(=O)NC(=O)/C=C\C(=O)NC(=O)C=C.C=Cc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
TSHR P16473 1/20 0.52
TGM2 P21980 2/20 0.48
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
KMT2A Q03164 1/20 0.42
PSMB11 A5LHX3 1/20 0.42
PSMA7 O14818 1/20 0.42
PSMB1 P20618 1/20 0.42
PSMA1 P25786 1/20 0.42
PSMA2 P25787 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7656834 0.85 HDAC2 (0.63) ALDH1A1HTTSMN1; SMN2HDAC3HDAC4
SCHEMBL831097 0.81 HDAC3 (0.67) ALDH1A1HTTSMN1; SMN2HDAC3HDAC4
Styrene SCHEMBL9776463 0.80 ALDH1A1 (0.50) ALDH1A1TSHRTGM2HDAC3HDAC4
Styrene SCHEMBL28863416 0.79 ALDH1A1 (0.54) ALDH1A1TSHRTGM2HDAC3HDAC4
Styrene SCHEMBL11036516 0.78 ALDH1A1 (0.40) ALDH1A1TSHRTGM2HTTSMN1; SMN2
Styrene SCHEMBL26133544 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTGM2SMN1; SMN2HDAC3
Styrene SCHEMBL17534942 0.78 TGM2 (0.81) ALDH1A1TSHRTGM2MMP1MMP2
Styrene SCHEMBL679822 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTGM2SMN1; SMN2HDAC3
Styrene SCHEMBL60237 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTGM2SMN1; SMN2HDAC3
Styrene SCHEMBL11061627 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTGM2SMN1; SMN2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0140519-A1 Use of chelating agents in water desalination PFIZER INC. (US) 1985-05-08 EP claimed
US-5631309-A MIXTURE OF DYE AND POLYMER WHICH CAN UNDERGO DECARBOXYLATION; WATERPROOFING; NONSCORCHING AND NONSTICKING KAO CORPORATION (JP) 1997-05-20 US disclosed