Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | IRS1 | P35568 | 1/20 | 0.32 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865324 | 0.92 | CYP4F2 (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865424 | 0.91 | RARA (0.37) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8874487 | 0.90 | PTGDR2 (0.31) | — | |
| SCHEMBL8864842 | 0.87 | RARA (0.37) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865035 | 0.87 | CYP3A4 (0.34) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL9843011 | 0.85 | PPARA (0.38) | — | |
| SCHEMBL8865408 | 0.85 | RARA (0.35) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL9284584 | 0.85 | CYP4F2 (0.35) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865814 | 0.85 | CYP3A4 (0.31) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865003 | 0.83 | RARA (0.30) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |