SCHEMBL8865294

SCHEMBL8865294

ClC1=C(Cl)C2(Cl)C3=C/C=C4C(=C\C=C/3C1(Cl)C2(Cl)Cl)\C1(Cl)C(Cl)=C(Cl)C\4(Cl)C1(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11458786 0.61 HSP90AA1 (1.00) HSP90AA1
SCHEMBL11458789 0.61 HSP90AA1 (0.38) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL11383299 0.59 HSP90AA1 (0.43) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL10452937 0.57 HSP90AA1 (0.34) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL10452148 0.57 HSP90AA1 (0.34) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL8371893 0.54 MEN1 (0.32) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL8371892 0.54 MEN1 (0.32) HSP90AA1MEN1THRBRECQLKMT2A
SCHEMBL7628890 0.53 MEN1 (0.38) MEN1THRBRECQLKMT2A
Dienochlor SCHEMBL117767 0.53 MEN1 (1.00) MEN1THRBRECQLKMT2A
SCHEMBL4830344 0.53 MEN1 (0.38) MEN1THRBRECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693410-A Ink jet transparencies XEROX CORPORATION (US) 1997-12-02 US claimed
US-5693410-A Ink jet transparencies XEROX CORPORATION (US) 1997-12-02 US disclosed