Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865363 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL8198625 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL8150869 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6218251 | 0.75 | — | — | |
| SCHEMBL8365133 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL17640940 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL8865607 | 0.74 | CA1 (0.40) | ALDH1A1MEN1KMT2ARNPEP | |
| SCHEMBL8865600 | 0.74 | CA1 (0.40) | ALDH1A1MEN1KMT2ARNPEP | |
| SCHEMBL20179252 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL21488669 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | claimed |
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |