Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865600 | 1.00 | CA1 (0.40) | CA1PLA2G10FOLH1P2RX7ALDH1A1 | |
| SCHEMBL8909364 | 0.76 | MEN1 (0.54) | CA1PLA2G10P2RX7ALDH1A1MEN1 | |
| SCHEMBL25507281 | 0.74 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1KMT2A | |
| SCHEMBL27105837 | 0.74 | PLA2G10 (0.47) | CA1PLA2G10ALDH1A1ANPEPRNPEP | |
| SCHEMBL20645392 | 0.74 | ALDH1A1 (0.46) | CA1PLA2G10FOLH1ALDH1A1MEN1 | |
| SCHEMBL5159794 | 0.74 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1KMT2A | |
| SCHEMBL8864988 | 0.74 | HPGD (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8864936 | 0.74 | HPGD (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8865366 | 0.74 | ALDH1A1 (0.54) | ALDH1A1RNPEPMEN1KMT2A | |
| SCHEMBL8865363 | 0.74 | ALDH1A1 (0.54) | ALDH1A1RNPEPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | claimed |
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |