Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865449 | 0.92 | APLNR (0.56) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL8642124 | 0.84 | APLNR (0.49) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL21125954 | 0.84 | APLNR (0.49) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL23743701 | 0.82 | HSD17B10 (0.46) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL29081751 | 0.82 | POLB (0.48) | APLNRHSD17B10POLBMEN1KMT2A | |
| Butane SCHEMBL8150861 | 0.82 | POLB (0.46) | HSD17B10POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL27621744 | 0.81 | APLNR (0.53) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL9091271 | 0.81 | TDP1 (0.50) | HSD17B10POLBKMT2AALDH1A1 | |
| SCHEMBL19860802 | 0.80 | APLNR (0.51) | APLNRHSD17B10POLBMEN1KMT2A | |
| SCHEMBL27728542 | 0.80 | HSD17B10 (0.59) | HSD17B10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| CN-1030918-C | 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1996-02-07 | — | — | CN | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |