Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865449 | 0.88 | APLNR (0.56) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL5834513 | 0.87 | ALDH1A1 (0.46) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL21125954 | 0.85 | APLNR (0.49) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL8865459 | 0.84 | APLNR (0.51) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL29081751 | 0.84 | POLB (0.48) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL27621744 | 0.83 | APLNR (0.53) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL19860802 | 0.81 | APLNR (0.51) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL11819760 | 0.81 | APLNR (0.51) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL28309457 | 0.79 | APLNR (0.53) | APLNRHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL23743701 | 0.78 | HSD17B10 (0.46) | APLNRHSD17B10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679652-B1 | Process for preparing carbapenem compounds | SUMITOMO PHARMA (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5578722-A | Process for preparing carbapenem compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0679652-A1 | Process for preparing carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-11-02 | — | — | EP | disclosed |