Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CYCS | P99999 | 3/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266268 | 0.85 | TERT (0.46) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL3999476 | 0.85 | TOP1 (0.54) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL4268731 | 0.85 | TERT (0.46) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL1639281 | 0.81 | TOP1 (0.50) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL8865610 | 0.81 | MMP3 (0.46) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL5918884 | 0.80 | TOP1 (0.55) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL30493184 | 0.80 | TOP1 (0.55) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL8909228 | 0.79 | GRIN2D (0.53) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL8908306 | 0.79 | TOP1 (0.48) | TERTTOP1STAT3STAT1CYCS | |
| SCHEMBL1640460 | 0.79 | TERT (0.50) | TERTTOP1STAT3STAT1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |
| US-5217966-A | Synthetic drug molecules that mimic metalloenzymes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-08 | — | — | US | disclosed |
| US-5202317-A | SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-04-13 | — | — | US | disclosed |