SCHEMBL8865597

SCHEMBL8865597

CCCOC(C)N1CCOC1=O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
PIK3CD O00329 2/20 0.38
NAAA Q02083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10550159 0.90 NAAA (0.41) KDM4EPIK3CDNAAA
SCHEMBL6551934 0.89 KDM4E (0.40) KDM4EPIK3CDNAAA
SCHEMBL8865227 0.86 KDM4E (0.43) KDM4EPIK3CDNAAA
SCHEMBL1056664 0.77 KDM4E (0.46) KDM4EPIK3CDNAAA
SCHEMBL7136148 0.76 KDM4E (0.38) KDM4EPIK3CDNAAA
SCHEMBL10732707 0.75 KDM4E (0.45) KDM4EPIK3CDNAAA
SCHEMBL22017454 0.74 KDM4E (0.44) KDM4EPIK3CDNAAA
SCHEMBL13330255 0.73 KDM4E (0.46) KDM4EPIK3CDNAAA
SCHEMBL6551930 0.72 KDM4E (0.43) KDM4EPIK3CDNAAA
SCHEMBL10413751 0.72 KDM4E (0.40) KDM4EPIK3CDNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700946-A ONE STEP CATALYTIC DEHYDROGENATION PROCESS OF N-(1-ALKOXYALKYL) COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1997-12-23 US disclosed
US-4857660-A ENZYME INHIBITORS, ANTICANCER AGENTS CIBA-GEIGY CORPORATION (US) 1989-08-15 US disclosed
US-4831153-A PYROLYZING (N-(1-HYDROXYALKYL) OR N-(1-HYDROCARBYLOXYALKYL))-2-OXAZOLIDINONE THE DOW CHEMICAL COMPANY (US) 1989-05-16 US disclosed
US-4764640-A AROMATOSE INHIBITOR CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed