Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423263 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL4586342 | 0.90 | ALDH1A1 (0.51) | SMN1; SMN2KDM4ECTBP2XDHALDH1A1 | |
| SCHEMBL4586337 | 0.90 | ALDH1A1 (0.51) | SMN1; SMN2KDM4ECTBP2XDHALDH1A1 | |
| SCHEMBL28291535 | 0.90 | CTBP2 (0.51) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL23410797 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL5095734 | 0.87 | L3MBTL1 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL6091876 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL6091878 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL4459267 | 0.87 | L3MBTL1 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 | |
| SCHEMBL4459265 | 0.87 | L3MBTL1 (0.47) | SMN1; SMN2KDM4ECTBP2XDHTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608069-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH GAMMA-AMINOBUTYRIC ACID | NOVO NORDISK A/S (DK) | 1997-03-04 | — | — | US | disclosed |