Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167532 | 0.96 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL28597541 | 0.96 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL11792372 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL3766375 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL8616123 | 0.88 | TSHR (0.52) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL28553598 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL9363446 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL11522848 | 0.85 | HTT (0.53) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL28362760 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL28590086 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285764-A | Treatment method for recycling (methyl) acrylic acid in esterification reaction system | 广东博兴新材料科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| EP-0523892-B1 | Cleaning compositions | BRITISH PETROLEUM CO PLC (GB) | 1994-12-28 | — | — | EP | claimed |
| EP-0136058-B1 | FLOW CYTOMETRY LYSING REAGENT WITH LEUKOPROTECTIVE AGENT FOR PRODUCING A 3-PART WBC COUNT | ORTHO DIAGNOSTIC SYSTEMS INC. (US) | 1990-11-22 | — | — | EP | claimed |
| US-4146454-A | EXCITATION, MOBILIZERS, INITIATORS | HABER INSTRUMENTS, INC. (US) | 1979-03-27 | — | — | US | claimed |
| US-12552783-B2 | Modulators of proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |
| CN-108472575-B | Method for increasing selectivity and capacity for capturing hydrogen sulfide from acid gas | 埃克森美孚研究工程公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113956779-A | Active energy ray-curable coating agent and coated building material using same | DIC油墨株式会社 | 2022-01-21 | — | — | CN | disclosed |
| US-11161841-B2 | Modulators of proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-11161841-B2 | Modulators of proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| EP-3774777-A2 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-109876858-B | Preparation method of (methyl) acrylate substance and application of 2-acrylamide-2-methylpropanesulfonic acid | 广东博兴新材料科技有限公司 | 2020-01-07 | — | — | CN | disclosed |
| US-20190315732-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2019-10-17 | — | — | US | disclosed |
| US-20190315732-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2019-10-17 | — | — | US | disclosed |
| CN-102482238-A | Novel conjugates, process for their preparation and their therapeutic use | SANOFI AVENTIS | 2012-05-30 | — | — | CN | disclosed |
| US-5631308-A | SELF-POLISHING METALLIZED COPOLYMER | KOREA CHEMICAL CO., LTD. (KR) | 1997-05-20 | — | — | US | disclosed |
| EP-0300107-A1 | Ester, thioester and amide derivatives of oxolinic acid, process for their synthesis and their therapeutical use | VETOQUINOL S.A. (FR) | 1989-01-25 | — | — | EP | disclosed |
| US-4048306-A | ANTIBACTERIAL | BOEHRINGER INGELHEIM GMBH (DT) | 1977-09-13 | — | — | US | disclosed |
| US-3951977-A | MINERAL OIL SOLUBLE, ANTIWEAR, ANTIRUST, DISPERSION DETERGENT ADDITIVES | STANDARD OIL COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315732-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | ALDH1A1 2958/4885TSHR 4501/4885MAPK1 3784/4885 |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | ALDH1A1 2958/4885TSHR 4501/4885MAPK1 3784/4885 |
| US-12552783-B2 | Modulators of proteolysis and associated methods of use | CRBN, ADRM1, MDM2 | ALDH1A1 3965/4885TSHR 2253/4885MAPK1 3100/4885 |
| US-11161841-B2 | Modulators of proteolysis and associated methods of use | MDM2, CRBN, VHL | ALDH1A1 2958/4885TSHR 4501/4885MAPK1 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.