Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.43 |
| ▸ | ACACA | Q13085 | 7/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 5/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866617 | 0.93 | ACACB (0.51) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8867162 | 0.92 | ACACB (0.38) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8866627 | 0.90 | IRAK1 (0.45) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8865702 | 0.89 | GBA1 (0.42) | ACACBACACATTK | |
| SCHEMBL9229561 | 0.87 | ACACB (0.41) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8866833 | 0.86 | CA12 (0.38) | TTKGPR119 | |
| SCHEMBL8867167 | 0.85 | ACACB (0.34) | ACACBACACATTKGPR119 | |
| SCHEMBL8866094 | 0.85 | ACACB (0.45) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8865835 | 0.84 | ACACB (0.49) | ACACBACACATTK | |
| SCHEMBL8866367 | 0.82 | ACACB (0.43) | ACACBACACATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |