Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.49 |
| ▸ | ACACA | Q13085 | 5/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866617 | 0.91 | ACACB (0.51) | ACACBACACATTK | |
| SCHEMBL8866094 | 0.85 | ACACB (0.45) | ACACBACACATTK | |
| SCHEMBL8866637 | 0.84 | WDR5 (0.42) | ACACBACACARORCWDR5EPHX2 | |
| SCHEMBL8866062 | 0.84 | ACACB (0.43) | ACACBACACATTK | |
| SCHEMBL9229561 | 0.84 | ACACB (0.41) | ACACBACACATTK | |
| SCHEMBL8866367 | 0.83 | ACACB (0.43) | ACACBACACAHDAC1TTK | |
| SCHEMBL8866110 | 0.81 | ACACB (0.41) | ACACBACACAWDR5TTK | |
| SCHEMBL8867162 | 0.79 | ACACB (0.38) | ACACBACACATTK | |
| SCHEMBL8866485 | 0.78 | ACACB (0.42) | ACACBACACAWDR5TTK | |
| SCHEMBL8866377 | 0.78 | ACACB (0.38) | ACACBACACATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |