Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 11/20 | 0.44 |
| ▸ | ACACA | Q13085 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 6/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866062 | 0.90 | ACACB (0.43) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8866617 | 0.84 | ACACB (0.51) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8867162 | 0.83 | ACACB (0.38) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8865702 | 0.80 | GBA1 (0.42) | ACACBACACACYP3A4 | |
| SCHEMBL9229561 | 0.79 | ACACB (0.41) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8866343 | 0.78 | USP30 (0.46) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8866094 | 0.78 | ACACB (0.45) | IRAK1ACACBACACACKS1BSKP1 | |
| SCHEMBL8867167 | 0.76 | ACACB (0.34) | ACACBACACA | |
| SCHEMBL8865835 | 0.76 | ACACB (0.49) | ACACBACACAWDR5 | |
| SCHEMBL8866833 | 0.76 | CA12 (0.38) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |